9B7B
Crystal structure of humanized 44H10 Fab Version 22 in complex with HLA-DR (HLA-DRA*01:01/HLA-DRB1*04:01)
Summary for 9B7B
Entry DOI | 10.2210/pdb9b7b/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, Hemagglutinin HA1 chain, HLA class II histocompatibility antigen DR beta chain, h44H10-V22 Antibody, heavy chain, ... (6 entities in total) |
Functional Keywords | antibody, humanized, mhc class ii, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 191261.77 |
Authors | |
Primary citation | Kassardjian, A.,Ivanochko, D.,Barber, B.,Jetha, A.,Julien, J.P. Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies, 13:-, 2024 Cited by PubMed: 39051333DOI: 10.3390/antib13030057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08 Å) |
Structure validation
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