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9B2G

Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NADH

Summary for 9B2G
Entry DOI10.2210/pdb9b2g/pdb
Related9B2F
DescriptorDehydrogenase/reductase SDR family member 9, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywordsshort-chain dehydrogenase reductase, oxylipins, polyunsaturated fatty acids, oxidoreductase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total formula weight71909.12
Authors
Pakhomova, S.,Belyaeva, O.V.,Boeglin, W.E.,Kedishvili, N.Y.,Brash, A.R.,Newcomer, M.E.,Popov, K.M. (deposition date: 2024-03-15, release date: 2025-03-19)
Primary citationPakhomova, S.,Belyaeva, O.V.,Boeglin, W.E.,Kedishvili, N.Y.,Brash, A.R.,Newcomer, M.E.,Popov, K.M.
The large substrate binding pocket of dehydrogenase reductase 9 underlies its ability to oxidize diverse pro-inflammatory and pro-resolving oxylipins.
To Be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

234785

PDB entries from 2025-04-16

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