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9B2F

Crystal structure of short chain dehydrogenase reductase 9 (short chain dehydrogenase reductase 9C4) in complex with NAD+

Summary for 9B2F
Entry DOI10.2210/pdb9b2f/pdb
Related9B2G
DescriptorDehydrogenase/reductase SDR family member 9, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, MALONATE ION, ... (4 entities in total)
Functional Keywordsshort-chain dehydrogenase reductase, oxylipins, polyunsaturated fatty acids, oxidoreductase
Biological sourceMus musculus (house mouse)
Total number of polymer chains1
Total formula weight36054.59
Authors
Pakhomova, S.,Belyaeva, O.V.,Boeglin, W.E.,Kedishvili, N.Y.,Brash, A.R.,Newcomer, M.E.,Popov, K.M. (deposition date: 2024-03-15, release date: 2025-03-19)
Primary citationPakhomova, S.,Belyaeva, O.V.,Boeglin, W.E.,Kedishvili, N.Y.,Brash, A.R.,Newcomer, M.E.,Popov, K.M.
The large substrate binding pocket of dehydrogenase reductase 9 underlies its ability to oxidize diverse pro-inflammatory and pro-resolving oxylipins.
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.662 Å)
Structure validation

236620

PDB entries from 2025-05-28

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