9B0C
Crystal structure of GenB2 in complex with gentamicin X2.
Summary for 9B0C
Entry DOI | 10.2210/pdb9b0c/pdb |
Related | 9AU3 9AUE |
Descriptor | 6'-epimerase, C-6' aminotransferase, (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total) |
Functional Keywords | gentamicin, plp-dependent enzymes, biosynthetic protein |
Biological source | Micromonospora echinospora |
Total number of polymer chains | 1 |
Total formula weight | 45396.36 |
Authors | Bury, P.S.,Araujo, N.C.,Oliveira, G.S.,Dias, M.V.B. (deposition date: 2024-03-11, release date: 2024-09-11, Last modification date: 2024-10-02) |
Primary citation | Oliveira, G.S.,Dos S Bury, P.,Huang, F.,Li, Y.,Araujo, N.C.,Zhou, J.,Sun, Y.,Leeper, F.J.,Leadlay, P.F.,Dias, M.V.B. Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 19:2002-2011, 2024 Cited by PubMed: 39207862DOI: 10.1021/acschembio.4c00334 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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