9AVA
Co-crystal structure of human TREX1 in complex with an inhibitor
This is a non-PDB format compatible entry.
Summary for 9AVA
Entry DOI | 10.2210/pdb9ava/pdb |
Descriptor | Three-prime repair exonuclease 1, POTASSIUM ION, (2R)-2-[(5R,6S,8R,9aS)-8-amino-1-oxo-5-(2-phenylethyl)hexahydro-1H-pyrrolo[1,2-a][1,4]diazepin-2(3H)-yl]-N-[(3,4-dichlorophenyl)methyl]-4-methylpentanamide, ... (5 entities in total) |
Functional Keywords | trex1, sgc, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 12 |
Total formula weight | 304787.27 |
Authors | Dehghani-Tafti, S.,Dong, A.,Li, Y.,Xu, J.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2024-03-01, release date: 2024-05-15) |
Primary citation | Dehghani-Tafti, S.,Dong, A.,Li, Y.,Xu, J.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) Co-crystal structure of human TREX1 in complex with an inhibitor To be published, |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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