8ZVP

Human SIRT6 in complex with EGCG

Summary for 8ZVP

• Entry DOI: 10.2210/pdb8zvp/pdb
• Descriptor: NAD-dependent protein deacylase sirtuin-6, ZINC ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (4 entities in total)
• Functional Keywords: complex inhibitor sirtuin, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 68400.42

Authors

Song, B.,Wang, Y. (deposition date: 2024-06-11, release date: 2025-06-18)

• Primary citation: Song, B.,Wang, Y.; SIRT6 in complex with EGCG; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)