8ZVP
Human SIRT6 in complex with EGCG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent protein deacylase sirtuin-6 | polymer | 299 | 33346.3 | 2 | UniProt (Q8N6T7) Pfam (PF02146) | Homo sapiens (human) | NAD-dependent protein deacetylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6,hSIRT6,SIR2-like protein 6 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 2 | Chemie (AR6) | |||
| 4 | E (A) | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | non-polymer | 458.4 | 1 | Chemie (KDH) |
Sequence modifications
A, B: 13 - 308 (UniProt: Q8N6T7)
| PDB | External Database | Details |
|---|---|---|
| Pro 10 | - | expression tag |
| Phe 11 | - | expression tag |
| Thr 12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66692.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1707.8 | |
| All* | Total formula weight | 68400.4 |
