8ZSS

Cryo-EM structure of the RO5263397-bound hTAAR1-Gs complex

This is a non-PDB format compatible entry.

Summary for 8ZSS

• Entry DOI: 10.2210/pdb8zss/pdb
• EMDB information: 60426
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, taar1, cryo-em, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 146247.96

Authors

Jiang, K.X.,Zheng, Y.,Xu, F. (deposition date: 2024-06-05, release date: 2024-07-24)

• Primary citation: Jiang, K.,Zheng, Y.,Zeng, L.,Wang, L.,Li, F.,Pu, J.,Lu, Y.,Zhao, S.,Xu, F.; The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules.; Cell Rep, 43:114505-114505, 2024; PubMed: 39002128; DOI: 10.1016/j.celrep.2024.114505

Experimental method

ELECTRON MICROSCOPY (3.07 Å)