8ZRT

Cryo-EM structure focused on the receptor of the ET-1 bound ETBR-DNGI complex

Summary for 8ZRT

• Entry DOI: 10.2210/pdb8zrt/pdb
• EMDB information: 60404
• Descriptor: Endothelin receptor type B, Endothelin-1 (2 entities in total)
• Functional Keywords: endothelin, receptor, gi, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 41306.21

Authors

Tani, K.,Maki-Yonekura, S.,Kanno, R.,Negami, T.,Hamaguchi, T.,Hall, M.,Mizoguchi, A.,Humbel, B.M.,Terada, T.,Yonekura, K.,Doi, T. (deposition date: 2024-06-05, release date: 2024-10-02)

• Primary citation: Tani, K.,Maki-Yonekura, S.,Kanno, R.,Negami, T.,Hamaguchi, T.,Hall, M.,Mizoguchi, A.,Humbel, B.M.,Terada, T.,Yonekura, K.,Doi, T.; Structure of endothelin ETB receptor-Gi complex in a conformation stabilized by the unique NPxxL motif; Commun Biol, 2024; DOI: 10.1038/s42003-024-06905-z

Experimental method

ELECTRON MICROSCOPY (3.62 Å)