8ZRK

Cryo-EM structure of GPR119-Gs Complex with small molecule agonist GSK-1292263

This is a non-PDB format compatible entry.

Summary for 8ZRK

• Entry DOI: 10.2210/pdb8zrk/pdb
• EMDB information: 60399
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpr119, gsk-1292263, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 154418.31

Authors

Wong, T.S.,Xiong, T.T.,Zeng, Z.C.,Gan, S.Y.,Qiu, C.,Du, Y. (deposition date: 2024-06-04, release date: 2024-06-19, Last modification date: 2025-07-16)

• Primary citation: Wong, T.S.,Xiong, T.T.,Zeng, Z.C.; Cryo-EM structure of GPR119-Gs complex; To be published,

Experimental method

ELECTRON MICROSCOPY (2.82 Å)