8ZL8

Structure of Polycystin-1/Polycystin-2 complex with 7b,27-DHC

Summary for 8ZL8

Entry DOI	10.2210/pdb8zl8/pdb
EMDB information	60222
Descriptor	Polycystin-1, Polycystin-2, (3~{S},7~{R},8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-10,13-dimethyl-17-[(2~{R},6~{R})-6-methyl-7-oxidanyl-heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthrene-3,7-diol, ... (4 entities in total)
Functional Keywords	ion channel, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	480925.60
Authors	Chen, M.Y.,Su, Q.,Shi, Y.G. (deposition date: 2024-05-17, release date: 2025-11-26)
Primary citation	Chen, M.Y.,Su, Q.,Shi, Y.G. Structure of Polycystin-1/Polycystin-2 complex with 7b,27-DHC To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.38 Å)

Structure validation