8ZL8
Structure of Polycystin-1/Polycystin-2 complex with 7b,27-DHC
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polycystin-1 | polymer | 1261 | 138514.7 | 1 | UniProt (P98161) Pfam (PF01477) Pfam (PF20519) Pfam (PF08016) | Homo sapiens (human) | PC1,Autosomal dominant polycystic kidney disease 1 protein |
| 2 | B, C, D (B, C, D) | Polycystin-2 | polymer | 1007 | 113555.0 | 3 | UniProt (Q13563) Pfam (PF20519) Pfam (PF00520) Pfam (PF08016) Pfam (PF18109) | Homo sapiens (human) | PC2,Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2 |
| 3 | E (A) | (3~{S},7~{R},8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-10,13-dimethyl-17-[(2~{R},6~{R})-6-methyl-7-oxidanyl-heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthrene-3,7-diol | non-polymer | 418.7 | 1 | Chemie (A1EQ3) | |||
| 4 | F, G, H, I, J... (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A: 3052 - 4303 (UniProt: P98161)
B, C, D: 1 - 968 (UniProt: Q13563)
| PDB | External Database | Details |
|---|---|---|
| Met 3043 | - | initiating methionine |
| Asp 3044 | - | expression tag |
| Tyr 3045 | - | expression tag |
| Lys 3046 | - | expression tag |
| Asp 3047 | - | expression tag |
| Asp 3048 | - | expression tag |
| Asp 3049 | - | expression tag |
| Asp 3050 | - | expression tag |
| Lys 3051 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -38 | - | initiating methionine |
| Gly -37 | - | expression tag |
| Ala -36 | - | expression tag |
| Ser -35 | - | expression tag |
| Ser -34 | - | expression tag |
| Ala -33 | - | expression tag |
| Trp -32 | - | expression tag |
| Ser -31 | - | expression tag |
| His -30 | - | expression tag |
| Pro -29 | - | expression tag |
| Gln -28 | - | expression tag |
| Phe -27 | - | expression tag |
| Glu -26 | - | expression tag |
| Lys -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Trp -12 | - | expression tag |
| Ser -11 | - | expression tag |
| His -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Gln -8 | - | expression tag |
| Phe -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | linker |
| Ala -2 | - | linker |
| Ala -1 | - | linker |
| Ala 0 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 479179.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1745.9 | |
| All* | Total formula weight | 480925.6 |
