8ZJ2

Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex

This is a non-PDB format compatible entry.

Summary for 8ZJ2

• Entry DOI: 10.2210/pdb8zj2/pdb
• Related: 8JHK 8XM7
• EMDB information: 60136
• Descriptor: Dedicator of cytokinesis protein 5, Ras-related C3 botulinum toxin substrate 1, Engulfment and cell motility protein 1, ... (6 entities in total)
• Functional Keywords: elmo, dock, gef, gtpase, rho, rac, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 615058.05

Authors

Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M. (deposition date: 2024-05-14, release date: 2024-06-26, Last modification date: 2024-07-17)

• Primary citation: Kukimoto-Niino, M.,Katsura, K.,Ishizuka-Katsura, Y.,Mishima-Tsumagari, C.,Yonemochi, M.,Inoue, M.,Nakagawa, R.,Kaushik, R.,Zhang, K.Y.J.,Shirouzu, M.; RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.; J.Biol.Chem., 300:107459-107459, 2024; PubMed: 38857861; DOI: 10.1016/j.jbc.2024.107459

Experimental method

ELECTRON MICROSCOPY (4.66 Å)