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8ZHG

SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, focused refinement of RBD-Fab region

Summary for 8ZHG
Entry DOI10.2210/pdb8zhg/pdb
Related8ZHD 8ZHE 8ZHF
EMDB information60102
DescriptorSpike glycoprotein,Fibritin,Expression Tag, Heavy chain of R1-26 Fab, Light chain of R1-26 Fab, ... (4 entities in total)
Functional Keywordsspike protein, rbd, antibody, fab, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
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Total number of polymer chains3
Total formula weight170348.18
Authors
Yan, Q.,Gao, X.,Liu, B.,Hou, R.,He, P.,Li, Z.,Chen, Q.,Wang, J.,He, J.,Chen, L.,Zhao, J.,Xiong, X. (deposition date: 2024-05-10, release date: 2024-08-21)
Primary citationYan, Q.,Gao, X.,Liu, B.,Hou, R.,He, P.,Ma, Y.,Zhang, Y.,Zhang, Y.,Li, Z.,Chen, Q.,Wang, J.,Huang, X.,Liang, H.,Zheng, H.,Yao, Y.,Chen, X.,Niu, X.,He, J.,Chen, L.,Zhao, J.,Xiong, X.
Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein helping to drive the genesis of Omicron variants
To Be Published,
Experimental method
Structure validation

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PDB entries from 2024-08-21

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