8ZH7

Crystal structure of N-terminal domain of N-methyl-D-aspartate receptor subunit NR1 in complex with patient-derived antibody

Summary for 8ZH7

• Entry DOI: 10.2210/pdb8zh7/pdb
• Descriptor: Glutamate receptor ionotropic, NMDA 1, Antibody #003-102 heavy chain, Antibody #003-102 light chain (3 entities in total)
• Functional Keywords: receptor, transmembrane, ion channel, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 377957.03

Authors

Nomura, N.,Kumazaki, K.,Amano, Y. (deposition date: 2024-05-10, release date: 2025-05-14)

• Primary citation: Kanno, A.,Kito, T.; Monoclonal humanized one-armed antibody blocking therapy for anti-NMDA receptor encephalitis; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.5 Å)