8ZH7
Crystal structure of N-terminal domain of N-methyl-D-aspartate receptor subunit NR1 in complex with patient-derived antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | Glutamate receptor ionotropic, NMDA 1 | polymer | 384 | 42620.4 | 4 | UniProt (Q05586) Pfam (PF01094) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, E, H, K (B, E, H, K) | Antibody #003-102 heavy chain | polymer | 250 | 26519.7 | 4 | Homo sapiens | ||
| 3 | C, F, I, L (C, F, I, L) | Antibody #003-102 light chain | polymer | 236 | 25349.1 | 4 | Homo sapiens |
Sequence modifications
A, D, G, J: 21 - 393 (UniProt: Q05586)
| PDB | External Database | Details |
|---|---|---|
| Val 394 | - | expression tag |
| Asp 395 | - | expression tag |
| Gly 396 | - | expression tag |
| Gly 397 | - | expression tag |
| Gly 398 | - | expression tag |
| Gly 399 | - | expression tag |
| Gly 400 | - | expression tag |
| Leu 401 | - | expression tag |
| Val 402 | - | expression tag |
| Pro 403 | - | expression tag |
| Arg 404 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 377957.0 | |
| All* | Total formula weight | 377957.0 |
