8ZBR

Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (apo-form)

8ZBR の概要

• エントリーDOI: 10.2210/pdb8zbr/pdb
• EMDBエントリー: 39908
• 分子名称: ATP-binding cassette sub-family C member 4, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE (3 entities in total)
• 機能のキーワード: atp-binding cassette sub-family c member 4, multidrug resistance proteins (mrps), multidrug-resistance (mdr), transport protein, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 155310.41

構造登録者

Xie, Z.,Long, F. (登録日: 2024-04-27, 公開日: 2025-04-09)

• 主引用文献: Xie, Z.,Long, F.; Structural insights into the human MRP4 mediating multiple drug resistance (MDR) to vincristine and 5-FU and reversal of MDR by lapatinib; To Be Published,

実験手法

ELECTRON MICROSCOPY (2.92 Å)