8Z6C

Crystal structure of HDGFRP2 PWWP domain in complex with 4-(4-bromo-1H-pyrazol-3-yl) pyridine

This is a non-PDB format compatible entry.

Summary for 8Z6C

• Entry DOI: 10.2210/pdb8z6c/pdb
• Descriptor: Hepatoma-derived growth factor-related protein 2, 4-(4-bromanyl-1~{H}-pyrazol-3-yl)pyridine, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hepatoma-derived growth factor-related protein 2, pwwp domain, hit, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 33124.04

Authors

Wei, X.,Ruan, K. (deposition date: 2024-04-19, release date: 2025-04-23)

• Primary citation: Wei, X.,Ruan, K.; Fragment based discovery of small molecule inhibitors of the HDGFRP2 PWWP domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.93 Å)