8Z54

Crystal structure of human SIRT5 in complex with succinylated Prx1 fragment

Summary for 8Z54

• Entry DOI: 10.2210/pdb8z54/pdb
• Descriptor: NAD-dependent protein deacylase sirtuin-5, mitochondrial, Peroxiredoxin-1 fragment, ZINC ION, ... (5 entities in total)
• Functional Keywords: sirt5, succinyl lysine, deacylase, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 31482.23

Authors

Yokoyama, T.,Takayama, Y. (deposition date: 2024-04-18, release date: 2024-10-09)

• Primary citation: Yokoyama, T.,Takayama, Y.,Mizuguchi, M.,Nabeshima, Y.,Kusaka, K.; SIRT5 mutants reveal the role of conserved asparagine and glutamine residues in the NAD + -binding pocket.; Febs Lett., 598:2269-2280, 2024; PubMed: 39031546; DOI: 10.1002/1873-3468.14961

Experimental method

X-RAY DIFFRACTION (1.45 Å)