8YZK

Orphan receptor GPRC5D in complex with scFv150-18

Summary for 8YZK

• Entry DOI: 10.2210/pdb8yzk/pdb
• EMDB information: 39696
• Descriptor: Soluble cytochrome b562,G-protein coupled receptor family C group 5 member D, scFv (2 entities in total)
• Functional Keywords: orphan receptor, gprc5d complex, scfv, membrane protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 156419.20

Authors

Yan, P.,Lin, X.,Xu, F. (deposition date: 2024-04-07, release date: 2024-07-03)

• Primary citation: Yan, P.,Lin, X.,Wu, L.,Xu, L.,Li, F.,Liu, J.,Xu, F.; The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer.; Nat Commun, 15:5255-5255, 2024; PubMed: 38898050; DOI: 10.1038/s41467-024-49625-y

Experimental method

ELECTRON MICROSCOPY (3.4 Å)