8YZK

Orphan receptor GPRC5D in complex with scFv150-18

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, B)	Soluble cytochrome b562,G-protein coupled receptor family C group 5 member D	polymer	421	47822.1	2	UniProt (P0ABE7) UniProt (Q9NZD1) Pfam (PF00003)	Escherichia coli	Cytochrome b-562
2	B, C (C, D)	scFv	polymer	288	30387.5	2		Homo sapiens (human)

Sequence modifications

A, B: -106 - 0 (UniProt: P0ABE7)

PDB	External Database	Details
Met -132	-	initiating methionine
Lys -131	-	expression tag
Thr -130	-	expression tag
Ile -129	-	expression tag
Ile -128	-	expression tag
Ala -127	-	expression tag
Leu -126	-	expression tag
Ser -125	-	expression tag
Tyr -124	-	expression tag
Ile -123	-	expression tag
Phe -122	-	expression tag
Cys -121	-	expression tag
Leu -120	-	expression tag
Val -119	-	expression tag
Phe -118	-	expression tag
Ala -117	-	expression tag
Asp -116	-	expression tag
Tyr -115	-	expression tag
Lys -114	-	expression tag
Asp -113	-	expression tag
Asp -112	-	expression tag
Asp -111	-	expression tag
Asp -110	-	expression tag
Ala -109	-	expression tag
Gly -108	-	expression tag
Arg -107	-	expression tag
Trp -99	Met 29	conflict
Ile -4	His 124	conflict
Leu 0	Arg 128	conflict

A, B: 1 - 268 (UniProt: Q9NZD1)

PDB	External Database	Details
Glu 269	-	expression tag
Phe 270	-	expression tag
Leu 271	-	expression tag
Glu 272	-	expression tag
Val 273	-	expression tag
Leu 274	-	expression tag
Phe 275	-	expression tag
Gln 276	-	expression tag
Gly 277	-	expression tag
Pro 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag
His 286	-	expression tag
His 287	-	expression tag
His 288	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	156419.2
All*	Total formula weight	156419.2

*Water molecules are not included.