8YXI

Crystal structure of SFTSV Gn in complex with a neutralizing antibody 40C10

Summary for 8YXI

• Entry DOI: 10.2210/pdb8yxi/pdb
• Descriptor: heavy chain, light chain, Envelopment polyprotein, ... (6 entities in total)
• Functional Keywords: neutralizing antibody, sftsv, complex, viral protein/immune system, viral protein-immune system complex
• Biological source: Severe fever with thrombocytopenia syndrome virus; More
• Total number of polymer chains: 3
• Total formula weight: 86847.85

Authors

Yang, P.,Guo, Y.,Zhang, N. (deposition date: 2024-04-02, release date: 2024-09-11, Last modification date: 2024-10-09)

• Primary citation: Yang, P.,Wu, X.,Shang, H.,Sun, Z.,Wang, Z.,Song, Z.,Yuan, H.,Deng, F.,Shen, S.,Guo, Y.,Zhang, N.; Molecular mechanism and structure-guided humanization of a broadly neutralizing antibody against SFTSV.; Plos Pathog., 20:-, 2024; PubMed: 39321193; DOI: 10.1371/journal.ppat.1012550

Experimental method

X-RAY DIFFRACTION (2.4 Å)