8YXI

Crystal structure of SFTSV Gn in complex with a neutralizing antibody 40C10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	heavy chain	polymer	222	23827.5	1		Mus musculus
2	B (B)	light chain	polymer	212	23512.0	1		Mus musculus
3	C (A)	Envelopment polyprotein	polymer	347	38497.4	1	UniProt (A0A2Z4HIM0) Pfam (PF07243)	Severe fever with thrombocytopenia syndrome virus	M polyprotein
4	D (D)	alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G62182OO)
5	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	F, G, H (C, B, A)	water	water		18.0	355	Chemie (HOH)

Sequence modifications

A: 1 - 321 (UniProt: A0A2Z4HIM0)

PDB	External Database	Details
Gly 322	-	expression tag
Leu 323	-	expression tag
Asn 324	-	expression tag
Asp 325	-	expression tag
Ile 326	-	expression tag
Phe 327	-	expression tag
Glu 328	-	expression tag
Ala 329	-	expression tag
Gln 330	-	expression tag
Lys 331	-	expression tag
Ile 332	-	expression tag
Glu 333	-	expression tag
Trp 334	-	expression tag
His 335	-	expression tag
Glu 336	-	expression tag
Ala 337	-	expression tag
Ala 338	-	expression tag
Ala 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	85836.9
Branched	Number of molecules	2
	Total formula weight	1010.9
All*	Total formula weight	86847.8

*Water molecules are not included.