8YX1
CD40 in complex with Bleselumab Fab
Summary for 8YX1
Entry DOI | 10.2210/pdb8yx1/pdb |
Descriptor | Bleselumab, heavy chain, Bleselumab, light chain, Tumor necrosis factor receptor superfamily member 5, ... (4 entities in total) |
Functional Keywords | cd40, dacetuzumab, bleselumab, agonist activity, tumor necrosis factor, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 134944.52 |
Authors | Caaveiro, J.M.M.,Fernandez-Perez, J.,Tsumoto, K. (deposition date: 2024-04-01, release date: 2024-05-08, Last modification date: 2024-05-22) |
Primary citation | Asano, R.,Nakakido, M.,Perez, J.F.,Ise, T.,Caaveiro, J.M.M.,Nagata, S.,Tsumoto, K. Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochem.Biophys.Res.Commun., 714:149969-149969, 2024 Cited by PubMed: 38657446DOI: 10.1016/j.bbrc.2024.149969 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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