8YRQ

Cryo-EM Structure of Human Protease-Activated Receptor 4 in complex with Gq heterotrimers and ScFv16 bound to Tethered Ligand

Summary for 8YRQ

• Entry DOI: 10.2210/pdb8yrq/pdb
• EMDB information: 39549
• Descriptor: Proteinase-activated receptor 4,Maltose/maltodextrin-binding periplasmic protein, Guanine nucleotide-binding protein mini G(o/q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total)
• Functional Keywords: gpcr, protease-activated receptor 4, membrane protein/immune system, tethered ligand, membrane protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 184587.52

Authors

Xu, Z.,Zhang, H. (deposition date: 2024-03-21, release date: 2026-06-10)

• Primary citation: Xu, Z.,Zhang, H.; Cryo-EM Structure of Human Protease-Activated Receptor 4 in complex with Gq heterotrimers bound to Tethered Ligand; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)