8YPE

The crystal structure of inactive p38 complexed with a ATF2 from 46 to 80

Summary for 8YPE

• Entry DOI: 10.2210/pdb8ype/pdb
• Descriptor: Cyclic AMP-dependent transcription factor ATF-2, Mitogen-activated protein kinase 14 (3 entities in total)
• Functional Keywords: map kinase p38 alpha, docking interactions, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 45594.06

Authors

Zhang, Y.Y.,Pei, C.J.,He, Q.Q.,Luo, Z.P.,Wu, J.W.,Wang, Z.X. (deposition date: 2024-03-16, release date: 2025-03-19)

• Primary citation: Zhang, Y.Y.,Pei, C.J.,He, Q.Q.,Luo, Z.P.,Wu, J.W.,Wang, Z.X.; Structural and mechanistic insights into the allosteric activation of p38alpha MAP kinase via specific docking interactions; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)