8YLW

Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with Lys-AMS

Summary for 8YLW

• Entry DOI: 10.2210/pdb8ylw/pdb
• Descriptor: Lysine--tRNA ligase, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE (3 entities in total)
• Functional Keywords: malaria, lysrs, lys-ams, lysyladenylate analog, inhibitor, ligase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 4
• Total formula weight: 236725.70

Authors

Sharma, V.K.,Manickam, Y.,Bagale, S.,Pradeepkumar, P.I.,Sharma, A. (deposition date: 2024-03-07, release date: 2025-09-10)

• Primary citation: Sharma, V.K.,Manickam, Y.,Bagale, S.,Pradeepkumar, P.I.,Sharma, A.; Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with Lys-AMS; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)