Summary for 8XZ7
Entry DOI | 10.2210/pdb8xz7/pdb |
Descriptor | Fibroblast growth factor receptor 1, SULFATE ION, 5-azanyl-3-[2-[4,6-bis(fluoranyl)-2-methyl-3~{H}-benzimidazol-5-yl]ethynyl]-1-[[3-(prop-2-enoylamino)phenyl]methyl]pyrazole-4-carboxamide, ... (4 entities in total) |
Functional Keywords | fibroblast growth factor receptor 1, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 71960.25 |
Authors | |
Primary citation | Deng, W.,Chen, X.,Liang, H.,Song, X.,Xiang, S.,Guo, J.,Tu, Z.,Zhou, Y.,Chen, Y.,Lu, X. Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors. Eur.J.Med.Chem., 275:116558-116558, 2024 Cited by PubMed: 38870833DOI: 10.1016/j.ejmech.2024.116558 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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