8X8Y

Crystal structure of ROCK2 with GNS-2660 inhibitor

Summary for 8X8Y

• Entry DOI: 10.2210/pdb8x8y/pdb
• Descriptor: Rho-associated protein kinase 2, 3-fluoranyl-~{N}-methyl-5-[[1-oxidanylidene-6-[5-(trifluoromethyl)-1~{H}-pyrazol-4-yl]isoquinolin-2-yl]methyl]benzamide (3 entities in total)
• Functional Keywords: inhibitor, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 90945.26

Authors

Park, T.H.,Bong, S.M.,Lee, S.J.,Lee, B.I. (deposition date: 2023-11-29, release date: 2024-12-04)

• Primary citation: Park, T.H.,Lee, B.I.; crystal structure of rock2 with GNS-2660 inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.2 Å)