8X8Y
Crystal structure of ROCK2 with GNS-2660 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Rho-associated protein kinase 2 | polymer | 391 | 45028.2 | 2 | UniProt (O75116) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | C, D (A, B) | 3-fluoranyl-~{N}-methyl-5-[[1-oxidanylidene-6-[5-(trifluoromethyl)-1~{H}-pyrazol-4-yl]isoquinolin-2-yl]methyl]benzamide | non-polymer | 444.4 | 2 | Chemie (YEA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90056.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 888.8 | |
| All* | Total formula weight | 90945.3 |
