8X62

crystal structure of human Mcl-1 kinase domain in complex with RM1

Summary for 8X62

• Entry DOI: 10.2210/pdb8x62/pdb
• Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, 1-[7-[1,5-dimethyl-3-(phenoxymethyl)pyrazol-4-yl]-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indol-2-yl]-2,2-bis(oxidanyl)ethanone (2 entities in total)
• Functional Keywords: inhibitor, teansferase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 35135.11

Authors

Zhang, Z.M.,Wang, L. (deposition date: 2023-11-20, release date: 2025-05-21)

• Primary citation: Zhang, Z.M.,Wang, L.; crystal structure of human Mcl-1 kinase domain in complex with RM1; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.80339461801 Å)