8X62
crystal structure of human Mcl-1 kinase domain in complex with RM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 151 | 17279.7 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (human) | |
| 2 | C (A) | 1-[7-[1,5-dimethyl-3-(phenoxymethyl)pyrazol-4-yl]-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indol-2-yl]-2,2-bis(oxidanyl)ethanone | non-polymer | 575.7 | 1 | Chemie (YO0) |
Sequence modifications
A, B: 172 - 321 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Ser 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34559.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 575.7 | |
| All* | Total formula weight | 35135.1 |
