8WYW

Crystal structure of spleen tyrosine kinase (SYK) in complex with SKI-O-592 (free form of SKI-O-703, cevidoplenib)

Summary for 8WYW

• Entry DOI: 10.2210/pdb8wyw/pdb
• Descriptor: Tyrosine-protein kinase SYK, SKI-O-592, GLYCEROL, ... (4 entities in total)
• Functional Keywords: transferase, signal pathway, anticancer
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 69471.94

Authors

Bong, S.M.,Lee, B.I. (deposition date: 2023-10-31, release date: 2024-11-06)

• Primary citation: Bong, S.M.,Lee, B.I.; Crystal structure of spleen tyrosine kinase (Syk) in complex with SKI-O-592 (free form of SKI-O-703, cevidoplenib); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)