8WMU

Structural basis of tubulin and heterocyclic podophyllotoxins complex for anticancer agents with dual-binding sites

This is a non-PDB format compatible entry.

Summary for 8WMU

• Entry DOI: 10.2210/pdb8wmu/pdb
• Descriptor: Detyrosinated tubulin alpha-1B chain, GUANOSINE-5'-DIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (15 entities in total)
• Functional Keywords: tublin, inhibitor, two binding sites, cell cycle
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 258491.01

Authors

Zhao, W.,Bi, J. (deposition date: 2023-10-04, release date: 2024-10-09)

• Primary citation: Zhao, W.; Structural basis of tubulin and heterocyclic podophyllotoxins complex for anticancer agents with dual-binding sites; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)