8W50

Crystal structure of DNA binding and cleavage core of human topoisomerase 2-alpha in a DNA binding-competent conformation

Summary for 8W50

• Entry DOI: 10.2210/pdb8w50/pdb
• Descriptor: DNA topoisomerase 2-alpha, SULFATE ION (3 entities in total)
• Functional Keywords: eukaryotic dna topoisomerase g-segment dna binding cleavage center assembly, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 371959.19

Authors

Chan, N.L.,Liu, K.T.,Chen, S.F. (deposition date: 2023-08-25, release date: 2024-07-24)

• Primary citation: Chan, N.L.,Liu, K.T.,Chen, S.F.; Structural Basis for the Assembly of Type IIA Topoisomerase DNA Cleavage/Religation Center; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.67 Å)