8W2H

Human liver phosphofructokinase-1 in the T-state conformation

Summary for 8W2H

Entry DOI	10.2210/pdb8w2h/pdb
EMDB information	43748
Descriptor	ATP-dependent 6-phosphofructokinase, liver type, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	pfk, glycolysis, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	348025.36
Authors	Lynch, E.M.,Kollman, J.M.,Webb, B.A. (deposition date: 2024-02-20, release date: 2024-09-11, Last modification date: 2024-09-25)
Primary citation	Lynch, E.M.,Hansen, H.,Salay, L.,Cooper, M.,Timr, S.,Kollman, J.M.,Webb, B.A. Structural basis for allosteric regulation of human phosphofructokinase-1. Nat Commun, 15:7323-7323, 2024 Cited by PubMed: 39183237 DOI: 10.1038/s41467-024-51808-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation