8W0Z

Human LCAD complexed with Lauric Acid

Summary for 8W0Z

• Entry DOI: 10.2210/pdb8w0z/pdb
• Related: 8W0T 8W0U
• Descriptor: Long-chain specific acyl-CoA dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, LAURIC ACID, ... (4 entities in total)
• Functional Keywords: fatty acid beta-oxidation, lcad, e291q, flavoprotein, cholesterol metabolism
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 8
• Total formula weight: 363837.04

Authors

Xia, C.,Kim, J.J.P. (deposition date: 2024-02-14, release date: 2024-06-19)

• Primary citation: Narayanan, B.,Xia, C.,McAndrew, R.,Shen, A.L.,Kim, J.P.; Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.; Sci Rep, 14:12976-12976, 2024; PubMed: 38839792; DOI: 10.1038/s41598-024-63027-6

Experimental method

X-RAY DIFFRACTION (2 Å)