8VYH

Crystal Structure Analysis of PARP1 in complex with a compound

This is a non-PDB format compatible entry.

Summary for 8VYH

• Entry DOI: 10.2210/pdb8vyh/pdb
• Descriptor: Poly [ADP-ribose] polymerase 1, processed C-terminus, (4S)-1-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}-4-hydroxy-L-proline, SULFATE ION, ... (4 entities in total)
• Functional Keywords: poly-adp-ribosyltransferase, dna repair, protein-inhibitor complex, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 80101.20

Authors

Seo, H.-S.,Dhe-Paganon, S.,Arthanari, H. (deposition date: 2024-02-08, release date: 2025-08-27)

• Primary citation: Seo, H.-S.,Dhe-Paganon, S.,Arthanari, H.; Crystal Structure Analysis of PARP1 in complex with a compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)