8VYH
Crystal Structure Analysis of PARP1 in complex with a compound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Poly [ADP-ribose] polymerase 1, processed C-terminus | polymer | 352 | 39351.0 | 2 | UniProt (P09874) Pfam (PF02877) Pfam (PF00644) | Homo sapiens (human) | Poly [ADP-ribose] polymerase 1,89-kDa form |
| 2 | C, H (A, B) | (4S)-1-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}-4-hydroxy-L-proline | non-polymer | 411.4 | 2 | Chemie (A1AEO) | |||
| 3 | D, E, F, G, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 527 | Chemie (HOH) |
Sequence modifications
A, B: 660 - 1011 (UniProt: P09874)
| PDB | External Database | Details |
|---|---|---|
| Pro 661 | Thr 661 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78702.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1399.1 | |
| All* | Total formula weight | 80101.2 |
