8VTA

SthK R120A in the presence of PIP2 and cAMP

Summary for 8VTA

Entry DOI	10.2210/pdb8vta/pdb
EMDB information	43521
Descriptor	Transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, ... (4 entities in total)
Functional Keywords	cyclic-nucleotide binding, potassium channel, lipid modulation, transport protein
Biological source	Spirochaeta thermophila
Total number of polymer chains	4
Total formula weight	227096.20
Authors	Schmidpeter, P.A.M.,Thon, O.,Nimigean, C.M. (deposition date: 2024-01-26, release date: 2024-09-25, Last modification date: 2024-10-02)
Primary citation	Thon, O.,Wang, Z.,Schmidpeter, P.A.M.,Nimigean, C.M. PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK. Nat Commun, 15:8230-8230, 2024 Cited by PubMed: 39300080 DOI: 10.1038/s41467-024-52469-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation