8VMF

Crystal structure of a transition-state mimic of the GSK-3/Axin complex bound to a beta-catenin S45D peptide

Summary for 8VMF

• Entry DOI: 10.2210/pdb8vmf/pdb
• Descriptor: Glycogen synthase kinase-3 beta, Axin-1, Catenin beta-1, ... (9 entities in total)
• Functional Keywords: gsk-3, kinase, transferase-signaling protein complex, transferase/signaling protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 48038.37

Authors

Enos, M.D.,Gavagan, M.,Jameson, N.,Zalatan, J.G.,Weis, W.I. (deposition date: 2024-01-13, release date: 2024-08-28)

• Primary citation: Enos, M.D.,Gavagan, M.,Jameson, N.,Zalatan, J.G.,Weis, W.I.; Structural and functional effects of phosphopriming and scaffolding in the kinase GSK3beta; Sci.Signal., 2024; DOI: 10.1126/scisignal.ado0881

Experimental method

X-RAY DIFFRACTION (2.5 Å)