8VEC
Deep Mutational Scanning of SARS-CoV-2 PLpro
Summary for 8VEC
Entry DOI | 10.2210/pdb8vec/pdb |
Descriptor | Papain-like protease nsp3, ZINC ION (3 entities in total) |
Functional Keywords | papain-like protease, sars-cov-2, mutation, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 1 |
Total formula weight | 36103.28 |
Authors | |
Primary citation | Wu, X.,Go, M.,Nguyen, J.V.,Kuchel, N.W.,Lu, B.G.C.,Lowes, K.N.,Calleja, D.J.,Mitchell, J.P.,Lessene, G.,Komander, D.,Call, M.E.,Call, M.J. Mutational Profiling of SARS-CoV-2 PLpro in human cells reveals requirements for function, structure, and drug escape Biorxiv, 2024 Cited by DOI: 10.1101/2024.03.11.584210PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report