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8VEC

Deep Mutational Scanning of SARS-CoV-2 PLpro

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APapain-like protease nsp3polymer31836037.91UniProt (P0DTD1)
Pfam (PF08715)
In PDB
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO
2AZINC IONnon-polymer65.41Chemie (ZN)
3waterwater18.0219Chemie (HOH)
Sequence modifications
A: 0 - 315 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Trp 208Met 1771engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36037.9
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight36103.3
*Water molecules are not included.

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PDB entries from 2024-09-04

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