8VDT

DNA Ligase 1 with nick DNA 3'rA:T

Summary for 8VDT

• Entry DOI: 10.2210/pdb8vdt/pdb
• Descriptor: DNA ligase 1, DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (5 entities in total)
• Functional Keywords: ligase, dna ligase 1, ligase-dna complex, ligase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 84171.38

Authors

KanalElamparithi, B.,Gulkis, M.,Caglayan, M. (deposition date: 2023-12-17, release date: 2024-05-22)

• Primary citation: Balu, K.E.,Gulkis, M.,Almohdar, D.,Caglayan, M.; Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA.; J.Biol.Chem., 300:107216-107216, 2024; PubMed: 38522520; DOI: 10.1016/j.jbc.2024.107216

Experimental method

X-RAY DIFFRACTION (2.78 Å)