8UW3
Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state
Summary for 8UW3
Entry DOI | 10.2210/pdb8uw3/pdb |
EMDB information | 42637 |
Descriptor | LINE-1 retrotransposable element ORF2 protein, Template RNA, Complementary DNA, ... (4 entities in total) |
Functional Keywords | line-1, retrotransposon, reverse transcriptase, retroelement, rna binding protein, rna, rna binding protein-rna-dna complex, rna binding protein/rna/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 177690.60 |
Authors | Thawani, A.,Florez Ariza, A.J.,Collins, K.,Nogales, E. (deposition date: 2023-11-06, release date: 2023-12-20, Last modification date: 2024-02-14) |
Primary citation | Thawani, A.,Ariza, A.J.F.,Nogales, E.,Collins, K. Template and target-site recognition by human LINE-1 in retrotransposition. Nature, 626:186-193, 2024 Cited by PubMed: 38096901DOI: 10.1038/s41586-023-06933-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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