8UT1

Alpha7-nicotinic acetylcholine receptor bound to epibatidine

Summary for 8UT1

• Entry DOI: 10.2210/pdb8ut1/pdb
• Related: 8UTB 8UZJ 8V80 8V82 8V86 8V88 8V89 8V8A 8V8C 8V8D
• EMDB information: 42526
• Descriptor: Neuronal acetylcholine receptor subunit alpha-7,Soluble cytochrome b562 fusion, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: ion channel, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 357633.73

Authors

Burke, S.M.,Hibbs, R.E.,Noviello, C.M. (deposition date: 2023-10-30, release date: 2024-02-21, Last modification date: 2024-03-13)

• Primary citation: Burke, S.M.,Avstrikova, M.,Noviello, C.M.,Mukhtasimova, N.,Changeux, J.P.,Thakur, G.A.,Sine, S.M.,Cecchini, M.,Hibbs, R.E.; Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation.; Cell, 187:1160-1176.e21, 2024; PubMed: 38382524; DOI: 10.1016/j.cell.2024.01.032

Experimental method

ELECTRON MICROSCOPY (2.3 Å)