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8UH2

Complex of C3b with the inhibitor albicin

Summary for 8UH2
Entry DOI10.2210/pdb8uh2/pdb
EMDB information42244
DescriptorAlbicin, Complement C3 beta chain, Complement C3b alpha' chain, ... (4 entities in total)
Functional Keywordscomplement, mosquito, c3, convertase, alternative pathway, immune system
Biological sourceAnopheles albimanus
More
Total number of polymer chains6
Total formula weight378261.92
Authors
Andersen, J.F.,Lei, H.,Strayer, E.,Ribeiro, J.M. (deposition date: 2023-10-06, release date: 2024-05-08)
Primary citationAndersen, J.F.,Lei, H.,Strayer, E.,Pham, V.,Ribeiro, J.M.
The mechanism of a mosquito salivary inhibitor of the alternative C3 convertase is elucidated through structural analysis of its complex with C3bBb
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.59 Å)
Structure validation

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PDB entries from 2024-05-15

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