8UH2
Complex of C3b with the inhibitor albicin
Functional Information from PROSITE/UniProt
| site_id | PS00477 |
| Number of Residues | 9 |
| Details | ALPHA_2_MACROGLOBULIN Alpha-2-macroglobulin family thiolester region signature. PsGCGEQnM |
| Chain | Residue | Details |
| B | PRO985-MET993 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by factor I => ECO:0000255 |
| Chain | Residue | Details |
| B | ARG932 | |
| H | ARG932 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by factor I |
| Chain | Residue | Details |
| B | ARG1281 | |
| B | ARG1298 | |
| H | ARG1281 | |
| H | ARG1298 | |
| G | SER16 | |
| G | SER48 | |
| G | SER275 | |
| G | SER281 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Coordinates Mg2+ for interaction with Complement factor B Bb fragment => ECO:0000269|PubMed:28264884, ECO:0000269|PubMed:31507604 |
| Chain | Residue | Details |
| B | ASN1641 | |
| H | ASN1641 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039 |
| Chain | Residue | Details |
| B | SER946 | |
| B | SER1299 | |
| B | SER1551 | |
| H | SER946 | |
| H | SER1299 | |
| H | SER1551 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17051150 |
| Chain | Residue | Details |
| B | ASN917 | |
| H | ASN917 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952 |
| Chain | Residue | Details |
| B | ASN1595 | |
| H | ASN1595 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln) |
| Chain | Residue | Details |
| B | CYS988 | |
| B | GLN991 | |
| H | CYS988 | |
| H | GLN991 |
