8U70

Crystal structure of malaria transmission-blocking anti-Pfs48/45 antibody RUPA-58.

Summary for 8U70

• Entry DOI: 10.2210/pdb8u70/pdb
• Descriptor: Antibody RUPA-58 Kappa chain, Antibody RUPA-58 Heavy chain (2 entities in total)
• Functional Keywords: pfs48/45, human transmission-blocking antibodies, malaria, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 287318.91

Authors

Hailemariam, S.,Ivanochko, D.,Julien, J.P. (deposition date: 2023-09-14, release date: 2024-09-18)

• Primary citation: Kucharska, I.,Ivanochko, D.,Hailemariam, S.,Inklaar, M.R.,Teelen, K.,Stoter, R.,van de Vegte-Bolmer, M.,van Gemert, G.J.,Semesi, A.,McLeod, B.,Rubinstein, J.,Jore, M.M.,Julien, J.P.; Structural elucidation of full-length Pfs48/45 in complex with potent mAbs isolated from a naturally exposed individual.; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.09 Å)