8U5G
Crystal structure of the co-expressed SDS22:PP1:I3 complex
Summary for 8U5G
Entry DOI | 10.2210/pdb8u5g/pdb |
Descriptor | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, Protein phosphatase 1 regulatory subunit 7, E3 ubiquitin-protein ligase PPP1R11, ... (6 entities in total) |
Functional Keywords | phosphatase, inhibitor, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 76622.30 |
Authors | Choy, M.S.,Peti, W.,Page, R. (deposition date: 2023-09-12, release date: 2023-12-06, Last modification date: 2024-01-03) |
Primary citation | Choy, M.S.,Srivastava, G.,Robinson, L.C.,Tatchell, K.,Page, R.,Peti, W. The SDS22:PP1:I3 complex: SDS22 binding to PP1 loosens the active site metal to prime metal exchange. J.Biol.Chem., 300:105515-105515, 2023 Cited by PubMed: 38042495DOI: 10.1016/j.jbc.2023.105515 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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